diff --git a/PC-optimization.md b/PC-optimization.md
index 36d2c34..b0f40b0 100644
--- a/PC-optimization.md
+++ b/PC-optimization.md
@@ -74,6 +74,7 @@ These won't help with stuttering, but may help with keeping a steady framerate,
 * Try using [Windows inbox audio driver](https://matthewvaneerde.wordpress.com/2010/08/23/troubleshooting-how-to-install-the-microsoft-hd-audio-class-driver/) - especially if you have a Realtek audio device, since their drivers can introduce higher latency. The typical minimum latency for Realtek's driver is 10ms, but Windows inbox driver can reach <3ms.
     * You may lose some features with this, however; e.g., Stereo Mix, multiple audio channel support, audio effects and filters, etc.
 * Try to disable `audio effects` in Windows audio settings, which may help with latency.
+* Motherboards with USB DAC as on-board audio will give you higher audio latency (see [Issue 501](https://github.com/spice2x/spice2x.github.io/issues/501). Prefer ones with Realtek HD audio.
 
 # Memory (RAM) and disk (hard drives)
 * Make sure you have enough RAM. 4gb isn't going to cut it these days, even on a minimal OS setup.